Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice

Cyclic AMP-responsive element-binding protein H (CREBH encoded by Creb3l3) is a transcription factor that regulates the expression of genes that control lipid and glucose metabolism as well as inflammation. CREBH is upregulated in the liver under conditions of overnutrition, and mice globally lackin...

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Autores principales: Krumm, Christopher S., Xu, Xu, Bare, Curtis J., Holman, Corey D., Kersten, Sander, Dow, Lukas E., Lee, Ann-Hwee, Cohen, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246594/
https://www.ncbi.nlm.nih.gov/pubmed/34023388
http://dx.doi.org/10.1016/j.jbc.2021.100815