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Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injury

Mitochondrial dysfunction is a fundamental challenge in septic cardiomyopathy. Mitophagy and the mitochondrial unfolded protein response (UPR(mt)) are the predominant stress-responsive and protective mechanisms involved in repairing damaged mitochondria. Although mitochondrial homeostasis requires t...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Jasper, Heinrich, Toan, Sam, Muid, David, Chang, Xing, Zhou, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246635/
https://www.ncbi.nlm.nih.gov/pubmed/34174558
http://dx.doi.org/10.1016/j.redox.2021.102049