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Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injury
Mitochondrial dysfunction is a fundamental challenge in septic cardiomyopathy. Mitophagy and the mitochondrial unfolded protein response (UPR(mt)) are the predominant stress-responsive and protective mechanisms involved in repairing damaged mitochondria. Although mitochondrial homeostasis requires t...
Autores principales: | Wang, Yue, Jasper, Heinrich, Toan, Sam, Muid, David, Chang, Xing, Zhou, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246635/ https://www.ncbi.nlm.nih.gov/pubmed/34174558 http://dx.doi.org/10.1016/j.redox.2021.102049 |
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