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Biopharmaceutical Characteristics of Nifurtimox Tablets for Age‐ and Body Weight‐Adjusted Dosing in Patients With Chagas Disease

Treatment of Chagas disease with nifurtimox requires age‐ and body weight‐adjusted dosing, resulting in complex dosing instructions. Appropriate formulations are needed for precise and compliant dosing, especially in pediatric patients. We characterized the biopharmaceutical features of a standard n...

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Detalles Bibliográficos
Autores principales: Stass, Heino, Feleder, Ethel, Garcia‐Bournissen, Facundo, Nagelschmitz, Johannes, Weimann, Boris, Yerino, Gustavo, Altcheh, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246722/
https://www.ncbi.nlm.nih.gov/pubmed/33029953
http://dx.doi.org/10.1002/cpdd.871