A physiologically validated rat model of term birth asphyxia with seizure generation after, not during, brain hypoxia

OBJECTIVE: Birth asphyxia (BA) is often associated with seizures that may exacerbate the ensuing hypoxic–ischemic encephalopathy. In rodent models of BA, exposure to hypoxia is used to evoke seizures, that commence already during the insult. This is in stark contrast to clinical BA, in which seizure...

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Detalles Bibliográficos
Autores principales: Ala‐Kurikka, Tommi, Pospelov, Alexey, Summanen, Milla, Alafuzoff, Aleksander, Kurki, Samu, Voipio, Juha, Kaila, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full‐length Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246723/
https://www.ncbi.nlm.nih.gov/pubmed/33338272
http://dx.doi.org/10.1111/epi.16790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246723/
https://www.ncbi.nlm.nih.gov/pubmed/33338272
http://dx.doi.org/10.1111/epi.16790

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