Cargando…

Head‐to‐head comparison of clinical performance of CSF phospho‐tau T181 and T217 biomarkers for Alzheimer's disease diagnosis

INTRODUCTION: Phosphorylated tau (p‐tau) in cerebrospinal fluid (CSF) is an established Alzheimer's disease (AD) biomarker. Novel immunoassays targeting N‐terminal and mid‐region p‐tau181 and p‐tau217 fragments are available, but head‐to‐head comparison in clinical settings is lacking. METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales: Karikari, Thomas K., Emeršič, Andreja, Vrillon, Agathe, Lantero‐Rodriguez, Juan, Ashton, Nicholas J., Kramberger, Milica Gregorič, Dumurgier, Julien, Hourregue, Claire, Čučnik, Saša, Brinkmalm, Gunnar, Rot, Uroš, Zetterberg, Henrik, Paquet, Claire, Blennow, Kaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246793/
https://www.ncbi.nlm.nih.gov/pubmed/33252199
http://dx.doi.org/10.1002/alz.12236