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Single‐cell molecular profiling provides a high‐resolution map of basophil and mast cell development

BACKGROUND: Basophils and mast cells contribute to the development of allergic reactions. Whereas these mature effector cells are extensively studied, the differentiation trajectories from hematopoietic progenitors to basophils and mast cells are largely uncharted at the single‐cell level. METHODS:...

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Detalles Bibliográficos
Autores principales: Hamey, Fiona K., Lau, Winnie W.Y., Kucinski, Iwo, Wang, Xiaonan, Diamanti, Evangelia, Wilson, Nicola K., Göttgens, Berthold, Dahlin, Joakim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246912/
https://www.ncbi.nlm.nih.gov/pubmed/33078414
http://dx.doi.org/10.1111/all.14633