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Monitoring alpha‐synuclein oligomerization and aggregation using bimolecular fluorescence complementation assays: What you see is not always what you get

Bimolecular fluorescence complementation (BiFC) was introduced a decade ago as a method to monitor alpha‐synuclein (α‐syn) oligomerization in intact cells. Since then, several α‐syn BiFC cellular assays and animal models have been developed based on the assumption that an increase in the fluorescent...

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Detalles Bibliográficos
Autores principales: Frey, Bryan, AlOkda, Abdelrahman, Jackson, Matthew P., Riguet, Nathan, Duce, James A., Lashuel, Hilal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246987/
https://www.ncbi.nlm.nih.gov/pubmed/32772367
http://dx.doi.org/10.1111/jnc.15147