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Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification
The release of interleukin (IL)‐1β from primary human monocytes in response to extracellular LPS occurs through the NACHT, LRR and PYD domains‐containing protein 3 (NLRP3) inflammasome. In primary monocytes, in response to LPS, NLRP3 inflammasome activation is characterized by an independence of K(+...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247003/ https://www.ncbi.nlm.nih.gov/pubmed/33145969 http://dx.doi.org/10.1111/febs.15619 |