Prevalence and potentially prognostic value of C‐circles associated with alternative lengthening of telomeres in canine appendicular osteosarcoma

Alternative lengthening of telomeres (ALT) is a telomerase‐independent telomere maintenance mechanism (TMM) with high prevalence in human osteosarcomas but remains unknown in canine osteosarcomas. The aim of this study was to evaluate the prevalence of ALT by detection of extra‐chromosomal circles o...

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Detalles Bibliográficos
Autores principales: Bicanova, Ludmila, Kreilmeier‐Berger, Theresa, Reifinger, Martin, Holzmann, Klaus, Kleiter, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247038/
https://www.ncbi.nlm.nih.gov/pubmed/33211388
http://dx.doi.org/10.1111/vco.12665