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Effects of polymorphic cytochrome P450 2A6 genotypes on chemoprevention against colorectal tumors in single Japanese cohort using daily low-dose aspirin: insights into future personalized treatments

BACKGROUND: A chemopreventive effect of low-dose aspirin against colorectal tumors was previously found in participants of two Japanese multicenter, double-blind, randomized, placebo-controlled clinical trials investigating the effects of daily aspirin (100 mg/day) for 0.7–2 years on tumor recurrenc...

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Detalles Bibliográficos
Autores principales: Yamazaki, Hiroshi, Shimizu, Makiko, Otani, Takahiro, Mizugaki, Ami, Mure, Kanae, Suzuki, Sadao, Ishikawa, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247130/
https://www.ncbi.nlm.nih.gov/pubmed/34193316
http://dx.doi.org/10.1186/s40780-021-00209-8