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Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics

Flaviviruses are enveloped single positive-stranded RNA viruses. The capsid (C), a structural protein of flavivirus, is dimeric and alpha-helical, with several special structural and functional features. The functions of the C protein go far beyond a structural role in virions. It is not only respon...

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Detalles Bibliográficos
Autores principales: Zhang, Xingcui, Zhang, Yanting, Jia, Renyong, Wang, Mingshu, Yin, Zhongqiong, Cheng, Anchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247181/
https://www.ncbi.nlm.nih.gov/pubmed/34193256
http://dx.doi.org/10.1186/s13567-021-00966-2