Superoxide Dismutase 1 in Health and Disease: How a Frontline Antioxidant Becomes Neurotoxic

Cu/Zn superoxide dismutase (SOD1) is a frontline antioxidant enzyme catalysing superoxide breakdown and is important for most forms of eukaryotic life. The evolution of aerobic respiration by mitochondria increased cellular production of superoxide, resulting in an increased reliance upon SOD1. Cons...

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Detalles Bibliográficos
Autores principales: Trist, Benjamin G., Hilton, James B., Hare, Dominic J., Crouch, Peter J., Double, Kay L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247289/
https://www.ncbi.nlm.nih.gov/pubmed/32144830
http://dx.doi.org/10.1002/anie.202000451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247289/
https://www.ncbi.nlm.nih.gov/pubmed/32144830
http://dx.doi.org/10.1002/anie.202000451

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