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Two tagging single‐nucleotide polymorphisms to capture HLA‐DRB1*07:01–DQA1*02:01–DQB1*02:02 haplotype associated with asparaginase hypersensitivity

AIMS: Asparaginase (ASP) hypersensitivity is a well‐known challenge in the treatment of lymphoblastic malignancies. In terms of cost considerations, the cheap native Escherichia coli ASP, the most immunogenic form of this medication, is used in the first line in middle‐income countries. Previously,...

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Detalles Bibliográficos
Autores principales: Kutszegi, Nóra, Gézsi, András, F. Semsei, Ágnes, Müller, Judit, Simon, Réka, Kovács, Erika Rozália, Hegedüs, Katalin, Kovács, Gábor T., Szalai, Csaba, Erdélyi, Dániel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247313/
https://www.ncbi.nlm.nih.gov/pubmed/33217039
http://dx.doi.org/10.1111/bcp.14664