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Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells

Purpose: Radiotherapy is a major modality for treatment of local advanced esophageal squamous cell carcinoma (ESCC). Hepatocyte nuclear factor 1-alpha (HNF1A) is involved in regulation of tumor cell proliferation, apoptosis, cycle distribution, invasion metastasis and chemical resistance. The aim of...

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Detalles Bibliográficos
Autores principales: Zou, Naiyi, Zhang, Xueyuan, Li, Shuguang, Li, Youmei, Zhao, Yan, Yang, Xingxiao, Zhu, Shuchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247383/
https://www.ncbi.nlm.nih.gov/pubmed/34234870
http://dx.doi.org/10.7150/jca.58023