Shikonin Inhibits Tumor Growth of ESCC by suppressing PKM2 mediated Aerobic Glycolysis and STAT3 Phosphorylation

Background: Shikonin, a small molecule inhibitor of pyruvate kinase 2 (PKM2), has been demonstrated to play the antitumor effect in various cancers. However, the specific effects and related regulatory mechanism of Shikonin in esophageal squamous cell carcinoma (ESCC) have not been clearly declared....

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Detalles Bibliográficos
Autores principales: Zhang, Qiqi, Liu, Qing, Zheng, Shutao, Liu, Tao, Yang, Lifei, Han, Xiujuan, Lu, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247391/
https://www.ncbi.nlm.nih.gov/pubmed/34234853
http://dx.doi.org/10.7150/jca.58494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247391/
https://www.ncbi.nlm.nih.gov/pubmed/34234853
http://dx.doi.org/10.7150/jca.58494

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