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Anaphylaxis to drugs: Overcoming mast cell unresponsiveness by fake antigens

Our understanding of IgE‐mediated drug allergy relies on the hapten concept, which is well established in inducing adaptive reactions of the immune system to small molecules like drugs. The role of hapten‐carrier adducts in re‐challenge reactions leading to mast cell degranulation and anaphylaxis is...

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Detalles Bibliográficos
Autor principal: Pichler, Werner J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247404/
https://www.ncbi.nlm.nih.gov/pubmed/32780486
http://dx.doi.org/10.1111/all.14554