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The Role of Cholesterol in α‐Synuclein and Lewy Body Pathology in GBA1 Parkinson's Disease

Parkinson's disease (PD) is a progressive neurodegenerative disease where dopaminergic neurons in the substantia nigra are lost, resulting in a decrease in striatal dopamine and, consequently, motor control. Dopaminergic degeneration is associated with the appearance of Lewy bodies, which conta...

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Detalles Bibliográficos
Autores principales: García‐Sanz, Patricia, M.F.G. Aerts, Johannes, Moratalla, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247417/
https://www.ncbi.nlm.nih.gov/pubmed/33219714
http://dx.doi.org/10.1002/mds.28396