Met(166)‐Glu(168) residues in human PrP β2‐α2 loop account for evolutionary resistance to prion infection

AIMS: The amino acid sequence of prion protein (PrP) is a key determinant in the transmissibility of prion diseases. While PrP sequence is highly conserved among mammalian species, minor changes in the PrP amino acid sequence may confer alterations in the transmissibility of prion diseases. Classica...

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Detalles Bibliográficos
Autores principales: Espinosa, Juan Carlos, Marín‐Moreno, Alba, Aguilar‐Calvo, Patricia, Torres, Juan María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247420/
https://www.ncbi.nlm.nih.gov/pubmed/33253417
http://dx.doi.org/10.1111/nan.12676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247420/
https://www.ncbi.nlm.nih.gov/pubmed/33253417
http://dx.doi.org/10.1111/nan.12676

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