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Sunitinib Treatment for Advanced Paraganglioma: Case Report of a Novel SDHD Gene Mutation Variant and Systematic Review of the Literature

BACKGROUND: Paragangliomas (PGLs) are neuroendocrine neoplasms arising from chromaffin cells of sympathetic or parasympathetic paraganglia. Systemic therapies have been used only in metastatic PGLs. Antiangiogenic agents, such as sunitinib, could be a viable therapeutic choice in the subgroup of pat...

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Detalles Bibliográficos
Autores principales: Sesti, Franz, Feola, Tiziana, Puliani, Giulia, Centello, Roberta, Di Vito, Valentina, Bagni, Oreste, Lenzi, Andrea, Isidori, Andrea M., Cantisani, Vito, Faggiano, Antongiulio, Giannetta, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247584/
https://www.ncbi.nlm.nih.gov/pubmed/34221997
http://dx.doi.org/10.3389/fonc.2021.677983