A disproportionate impact of G9a methyltransferase deficiency on the X chromosome

G9a is a histone methyltransferase responsible for the dimethylation of histone H3 at lysine 9 (H3K9me2). G9a plays key roles in transcriptional silencing of developmentally regulated genes, but its role in X-chromosome inactivation (XCI) has been under debate. Here, we uncover a female-specific fun...

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Detalles Bibliográficos
Autores principales: Szanto, Attila, Aguilar, Rodrigo, Kesner, Barry, Blum, Roy, Wang, Danni, Cifuentes-Rojas, Catherine, del Rosario, Brian C., Kis-Toth, Katalin, Lee, Jeannie T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247598/
https://www.ncbi.nlm.nih.gov/pubmed/34168040
http://dx.doi.org/10.1101/gad.337592.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247598/
https://www.ncbi.nlm.nih.gov/pubmed/34168040
http://dx.doi.org/10.1101/gad.337592.120

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