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Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis

Autophagy inhibitors are currently being evaluated in clinical trials for the treatment of diverse cancers, largely due to their ability to impede tumor cell survival and metabolic adaptation. More recently, there is growing interest in whether and how modulating autophagy in the host stroma influen...

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Detalles Bibliográficos
Autores principales: Rudnick, Jenny A., Monkkonen, Teresa, Mar, Florie A., Barnes, James M., Starobinets, Hanna, Goldsmith, Juliet, Roy, Srirupa, Bustamante Eguiguren, Sofía, Weaver, Valerie M., Debnath, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247603/
https://www.ncbi.nlm.nih.gov/pubmed/34168038
http://dx.doi.org/10.1101/gad.345629.120