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Epitranscriptomic addition of m(6)A regulates HIV-1 RNA stability and alternative splicing

Previous work has demonstrated that the epitranscriptomic addition of m(6)A to viral transcripts can promote the replication and pathogenicity of a wide range of DNA and RNA viruses, including HIV-1, yet the underlying mechanisms responsible for this effect have remained unclear. It is known that m(...

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Detalles Bibliográficos
Autores principales: Tsai, Kevin, Bogerd, Hal P., Kennedy, Edward M., Emery, Ann, Swanstrom, Ronald, Cullen, Bryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247604/
https://www.ncbi.nlm.nih.gov/pubmed/34140354
http://dx.doi.org/10.1101/gad.348508.121