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Hierarchical reactivation of transcription during mitosis-to-G1 transition by Brn2 and Ascl1 in neural stem cells

During mitosis, chromatin condensation is accompanied by a global arrest of transcription. Recent studies suggest transcriptional reactivation upon mitotic exit occurs in temporally coordinated waves, but the underlying regulatory principles have yet to be elucidated. In particular, the contribution...

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Detalles Bibliográficos
Autores principales: Soares, Mário A.F., Soares, Diogo S., Teixeira, Vera, Heskol, Abeer, Bressan, Raul Bardini, Pollard, Steven M., Oliveira, Raquel A., Castro, Diogo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247608/
https://www.ncbi.nlm.nih.gov/pubmed/34168041
http://dx.doi.org/10.1101/gad.348174.120