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Synthesis and Cell Growth Inhibitory Activity of Six Non‐glycosaminoglycan‐Type Heparin‐Analogue Trisaccharides

The design and synthesis of heparin mimetics with high anticancer activity but no anticoagulant activity is an important task in medicinal chemistry. Herein, we present the efficient synthesis of five Glc‐GlcA‐Glc‐sequenced and one Glc‐IdoA‐Glc‐sequenced non‐glycosaminoglycan, heparin‐related trisac...

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Detalles Bibliográficos
Autores principales: Lisztes, Erika, Mező, Erika, Demeter, Fruzsina, Horváth, Lilla, Bősze, Szilvia, István Tóth, Balázs, Borbás, Anikó, Herczeg, Mihály
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247843/
https://www.ncbi.nlm.nih.gov/pubmed/33433040
http://dx.doi.org/10.1002/cmdc.202000917