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Assessing efficacy in important subgroups in confirmatory trials: An example using Bayesian dynamic borrowing
Assessment of efficacy in important subgroups – such as those defined by sex, age, race and region – in confirmatory trials is typically performed using separate analysis of the specific subgroup. This ignores relevant information from the complementary subgroup. Bayesian dynamic borrowing uses an i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247867/ https://www.ncbi.nlm.nih.gov/pubmed/33475231 http://dx.doi.org/10.1002/pst.2093 |