Effects of mutant huntingtin inactivation on Huntington disease‐related behaviours in the BACHD mouse model

AIMS: Huntington disease (HD) is a fatal neurodegenerative disorder with no disease‐modifying treatments approved so far. Ongoing clinical trials are attempting to reduce huntingtin (HTT) expression in the central nervous system (CNS) using different strategies. Yet, the distribution and timing of H...

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Detalles Bibliográficos
Autores principales: Cheong, Rachel Y., Baldo, Barbara, Sajjad, Muhammad U., Kirik, Deniz, Petersén, Åsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247873/
https://www.ncbi.nlm.nih.gov/pubmed/33330988
http://dx.doi.org/10.1111/nan.12682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247873/
https://www.ncbi.nlm.nih.gov/pubmed/33330988
http://dx.doi.org/10.1111/nan.12682

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