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Increasing the resolution and precision of psychiatric genome‐wide association studies by re‐imputing summary statistics using a large, diverse reference panel

Genotype imputation across populations of mixed ancestry is critical for optimal discovery in large‐scale genome‐wide association studies (GWAS). Methods for direct imputation of GWAS summary‐statistics were previously shown to be practically as accurate as summary statistics produced after raw geno...

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Detalles Bibliográficos
Autores principales: Chatzinakos, Chris, Lee, Donghyung, Cai, Na, Vladimirov, Vladimir I., Webb, Bradley T., Riley, Brien P., Flint, Jonathan, Kendler, Kenneth S., Ressler, Kerry J., Daskalakis, Nikolaos P., Bacanu, Silviu‐Alin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247874/
https://www.ncbi.nlm.nih.gov/pubmed/33576176
http://dx.doi.org/10.1002/ajmg.b.32834