Sister chromatid cohesion defects are associated with chromosomal copy number heterogeneity in high hyperdiploid childhood acute lymphoblastic leukemia

High hyperdiploid acute lymphoblastic leukemia (ALL) is one of the most common malignancies in children. The main driver event of this disease is a nonrandom aneuploidy consisting of gains of whole chromosomes but without overt evidence of chromosomal instability (CIN). Here, we investigated the fre...

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Detalles Bibliográficos
Autores principales: Moura‐Castro, Larissa H., Peña‐Martínez, Pablo, Castor, Anders, Galeev, Roman, Larsson, Jonas, Järås, Marcus, Yang, Minjun, Paulsson, Kajsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247877/
https://www.ncbi.nlm.nih.gov/pubmed/33368842
http://dx.doi.org/10.1002/gcc.22933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247877/
https://www.ncbi.nlm.nih.gov/pubmed/33368842
http://dx.doi.org/10.1002/gcc.22933

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