Reactive astrocytes as treatment targets in Alzheimer's disease—Systematic review of studies using the APPswePS1dE9 mouse model

Astrocytes regulate synaptic communication and are essential for proper brain functioning. In Alzheimer's disease (AD) astrocytes become reactive, which is characterized by an increased expression of intermediate filament proteins and cellular hypertrophy. Reactive astrocytes are found in close...

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Detalles Bibliográficos
Autores principales: Smit, Tamar, Deshayes, Natasja A. C., Borchelt, David R., Kamphuis, Willem, Middeldorp, Jinte, Hol, Elly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247905/
https://www.ncbi.nlm.nih.gov/pubmed/33634529
http://dx.doi.org/10.1002/glia.23981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247905/
https://www.ncbi.nlm.nih.gov/pubmed/33634529
http://dx.doi.org/10.1002/glia.23981

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