Pentafluoro‐3‐hydroxy‐pent‐2‐en‐1‐ones Potently Inhibit FNT‐Type Lactate Transporters from all Five Human‐Pathogenic Plasmodium Species

The protozoan parasite Plasmodium falciparum causes the most severe and prevailing form of malaria in sub‐Saharan Africa. Previously, we identified the plasmodial lactate transporter, PfFNT, a member of the microbial formate–nitrite transporter family, as a novel antimalarial drug target. With the p...

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Detalles Bibliográficos
Autores principales: Walloch, Philipp, Hansen, Christian, Priegann, Till, Schade, Dennis, Beitz, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247949/
https://www.ncbi.nlm.nih.gov/pubmed/33336890
http://dx.doi.org/10.1002/cmdc.202000952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247949/
https://www.ncbi.nlm.nih.gov/pubmed/33336890
http://dx.doi.org/10.1002/cmdc.202000952

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