Acetazolamide Improves Right Ventricular Function and Metabolic Gene Dysregulation in Experimental Pulmonary Arterial Hypertension

Background: Right ventricular (RV) performance is a key determinant of mortality in pulmonary arterial hypertension (PAH). RV failure is characterized by metabolic dysregulation with unbalanced anaerobic glycolysis, oxidative phosphorylation, and fatty acid oxidation (FAO). We previously found that...

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Detalles Bibliográficos
Autores principales: Spyropoulos, Fotios, Michael, Zoe, Finander, Benjamin, Vitali, Sally, Kosmas, Kosmas, Zymaris, Panagiotis, Kalish, Brian T., Kourembanas, Stella, Christou, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247952/
https://www.ncbi.nlm.nih.gov/pubmed/34222363
http://dx.doi.org/10.3389/fcvm.2021.662870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247952/
https://www.ncbi.nlm.nih.gov/pubmed/34222363
http://dx.doi.org/10.3389/fcvm.2021.662870

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