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Acetazolamide Improves Right Ventricular Function and Metabolic Gene Dysregulation in Experimental Pulmonary Arterial Hypertension
Background: Right ventricular (RV) performance is a key determinant of mortality in pulmonary arterial hypertension (PAH). RV failure is characterized by metabolic dysregulation with unbalanced anaerobic glycolysis, oxidative phosphorylation, and fatty acid oxidation (FAO). We previously found that...
Autores principales: | Spyropoulos, Fotios, Michael, Zoe, Finander, Benjamin, Vitali, Sally, Kosmas, Kosmas, Zymaris, Panagiotis, Kalish, Brian T., Kourembanas, Stella, Christou, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247952/ https://www.ncbi.nlm.nih.gov/pubmed/34222363 http://dx.doi.org/10.3389/fcvm.2021.662870 |
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