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Engineered Sortases in Peptide and Protein Chemistry

The transpeptidase sortase A of Staphylococcus aureus (Sa‐SrtA) is a valuable tool in protein chemistry. The native enzyme anchors surface proteins containing a highly conserved LPxTG sorting motif to a terminal glycine residue of the peptidoglycan layer in Gram‐positive bacteria. This reaction is e...

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Detalles Bibliográficos
Autores principales: Freund, Christian, Schwarzer, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248031/
https://www.ncbi.nlm.nih.gov/pubmed/33290621
http://dx.doi.org/10.1002/cbic.202000745