MRI‐assessed locus coeruleus integrity is heritable and associated with multiple cognitive domains, mild cognitive impairment, and daytime dysfunction

INTRODUCTION: The locus coeruleus (LC) undergoes extensive neurodegeneration in early Alzheimer's disease (AD). The LC is implicated in regulating the sleep–wake cycle, modulating cognitive function, and AD progression. METHODS: Participants were 481 men (ages 62 to 71.7) from the Vietnam Era T...

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Detalles Bibliográficos
Autores principales: Elman, Jeremy A., Puckett, Olivia K., Beck, Asad, Fennema‐Notestine, Christine, Cross, Latonya K., Dale, Anders M., Eglit, Graham M. L., Eyler, Lisa T., Gillespie, Nathan A., Granholm, Eric L., Gustavson, Daniel E., Hagler, Donald J., Hatton, Sean N., Hauger, Richard, Jak, Amy J., Logue, Mark W., McEvoy, Linda K., McKenzie, Ruth E., Neale, Michael C., Panizzon, Matthew S., Reynolds, Chandra A., Sanderson‐Cimino, Mark, Toomey, Rosemary, Tu, Xin M., Whitsel, Nathan, Williams, McKenna E., Xian, Hong, Lyons, Michael J., Franz, Carol E., Kremen, William S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248066/
https://www.ncbi.nlm.nih.gov/pubmed/33580733
http://dx.doi.org/10.1002/alz.12261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248066/
https://www.ncbi.nlm.nih.gov/pubmed/33580733
http://dx.doi.org/10.1002/alz.12261

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