The selective inhibitor of nuclear export (SINE) verdinexor exhibits biologic activity against canine osteosarcoma cell lines

Verdinexor (KPT‐335) is a novel orally bioavailable selective inhibitor of nuclear export (SINE) compound that inhibits the function of the nuclear export protein Exportin 1 (XPO1/CRM1). In the present study, we sought to characterize the expression of XPO1 in primary canine osteosarcoma (OS) tumour...

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Detalles Bibliográficos
Autores principales: Breitbach, Justin T., Louke, Darian S., Tobin, Savannah J., Watts, Mauria R., Davies, Alexander E., Fenger, Joelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248106/
https://www.ncbi.nlm.nih.gov/pubmed/33438820
http://dx.doi.org/10.1111/vco.12680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248106/
https://www.ncbi.nlm.nih.gov/pubmed/33438820
http://dx.doi.org/10.1111/vco.12680

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