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Action of Dipeptidyl Peptidase‐4 Inhibitors on SARS‐CoV‐2 Main Protease

In a recent publication, Eleftheriou et al. proposed that inhibitors of dipeptidyl peptidase‐4 (DPP‐4) are functional inhibitors of the main protease (M(pro)) of SARS‐CoV‐2. Their predictions prompted the authors to suggest linagliptin, a DPP‐4 inhibitor and approved anti‐diabetes drug, as a repurpo...

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Detalles Bibliográficos
Autores principales: Nar, Herbert, Schnapp, Gisela, Hucke, Oliver, Hardman, Timothy C., Klein, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248156/
https://www.ncbi.nlm.nih.gov/pubmed/33348462
http://dx.doi.org/10.1002/cmdc.202000921