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Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease

Intron retention (IR) has been implicated in the pathogenesis of complex diseases such as cancers; its association with Alzheimer's disease (AD) remains unexplored. We performed genome‐wide analysis of IR through integrating genetic, transcriptomic, and proteomic data of AD subjects and mouse m...

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Detalles Bibliográficos
Autores principales: Li, Hong‐Dong, Funk, Cory C., McFarland, Karen, Dammer, Eric B., Allen, Mariet, Carrasquillo, Minerva M., Levites, Yona, Chakrabarty, Paramita, Burgess, Jeremy D., Wang, Xue, Dickson, Dennis, Seyfried, Nicholas T., Duong, Duc M., Lah, James J., Younkin, Steven G., Levey, Allan I., Omenn, Gilbert S., Ertekin‐Taner, Nilüfer, Golde, Todd E., Price, Nathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248162/
https://www.ncbi.nlm.nih.gov/pubmed/33480174
http://dx.doi.org/10.1002/alz.12254