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Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease
Intron retention (IR) has been implicated in the pathogenesis of complex diseases such as cancers; its association with Alzheimer's disease (AD) remains unexplored. We performed genome‐wide analysis of IR through integrating genetic, transcriptomic, and proteomic data of AD subjects and mouse m...
Autores principales: | Li, Hong‐Dong, Funk, Cory C., McFarland, Karen, Dammer, Eric B., Allen, Mariet, Carrasquillo, Minerva M., Levites, Yona, Chakrabarty, Paramita, Burgess, Jeremy D., Wang, Xue, Dickson, Dennis, Seyfried, Nicholas T., Duong, Duc M., Lah, James J., Younkin, Steven G., Levey, Allan I., Omenn, Gilbert S., Ertekin‐Taner, Nilüfer, Golde, Todd E., Price, Nathan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248162/ https://www.ncbi.nlm.nih.gov/pubmed/33480174 http://dx.doi.org/10.1002/alz.12254 |
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