Autonomous TGFβ signaling induces phenotypic variation in human acute myeloid leukemia

Heterogeneity of leukemia stem cells (LSCs) is involved in their collective chemoresistance. To eradicate LSCs, it is necessary to understand the mechanisms underlying their heterogeneity. Here, we aimed to identify signals responsible for heterogeneity and variation of LSCs in human acute myeloid l...

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Detalles Bibliográficos
Autores principales: Shingai, Yasuhiro, Yokota, Takafumi, Okuzaki, Daisuke, Sudo, Takao, Ishibashi, Tomohiko, Doi, Yukiko, Ueda, Tomoaki, Ozawa, Takayuki, Nakai, Ritsuko, Tanimura, Akira, Ichii, Michiko, Shibayama, Hirohiko, Kanakura, Yuzuru, Hosen, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Cancer Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248163/
https://www.ncbi.nlm.nih.gov/pubmed/33539590
http://dx.doi.org/10.1002/stem.3348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248163/
https://www.ncbi.nlm.nih.gov/pubmed/33539590
http://dx.doi.org/10.1002/stem.3348

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