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Autonomous TGFβ signaling induces phenotypic variation in human acute myeloid leukemia
Heterogeneity of leukemia stem cells (LSCs) is involved in their collective chemoresistance. To eradicate LSCs, it is necessary to understand the mechanisms underlying their heterogeneity. Here, we aimed to identify signals responsible for heterogeneity and variation of LSCs in human acute myeloid l...
Autores principales: | Shingai, Yasuhiro, Yokota, Takafumi, Okuzaki, Daisuke, Sudo, Takao, Ishibashi, Tomohiko, Doi, Yukiko, Ueda, Tomoaki, Ozawa, Takayuki, Nakai, Ritsuko, Tanimura, Akira, Ichii, Michiko, Shibayama, Hirohiko, Kanakura, Yuzuru, Hosen, Naoki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248163/ https://www.ncbi.nlm.nih.gov/pubmed/33539590 http://dx.doi.org/10.1002/stem.3348 |
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