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Function and Mechanism of Trimetazidine in Myocardial Infarction-Induced Myocardial Energy Metabolism Disorder Through the SIRT1–AMPK Pathway

Myocardial energy metabolism (MEM) is an important factor of myocardial injury. Trimetazidine (TMZ) provides protection against myocardial ischemia/reperfusion injury. The current study set out to evaluate the effect and mechanism of TMZ on MEM disorder induced by myocardial infarction (MI). Firstly...

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Detalles Bibliográficos
Autores principales: Luo, Xiu-ying, Zhong, Ze, Chong, Ai-guo, Zhang, Wei-wei, Wu, Xin-dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248253/
https://www.ncbi.nlm.nih.gov/pubmed/34220528
http://dx.doi.org/10.3389/fphys.2021.645041