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A Retrospective Case Series Analysis of the Relationship Between Phenylalanine: Tyrosine Ratio and Cerebral Glucose Metabolism in Classical Phenylketonuria and Hyperphenylalaninemia

We retrospectively examined the relationship between blood biomarkers, in particular the historical mean phenylalanine to tyrosine (Phe:Tyr) ratio, and cerebral glucose metabolism. We hypothesized that the historical mean Phe:Tyr ratio would be more predictive of cerebral glucose metabolism than the...

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Detalles Bibliográficos
Autores principales: McGinnity, Colm J., Riaño Barros, Daniela A., Guedj, Eric, Girard, Nadine, Symeon, Christopher, Walker, Helen, Barrington, Sally F., Summers, Mary, Pitkanen, Mervi, Rahman, Yusof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248344/
https://www.ncbi.nlm.nih.gov/pubmed/34220424
http://dx.doi.org/10.3389/fnins.2021.664525