Activation, Structure, Biosynthesis and Bioactivity of Glidobactin‐like Proteasome Inhibitors from Photorhabdus laumondii

The glidobactin‐like natural products (GLNPs) glidobactin A and cepafungin I have been reported to be potent proteasome inhibitors and are regarded as promising candidates for anticancer drug development. Their biosynthetic gene cluster (BGC) plu1881–1877 is present in entomopathogenic Photorhabdus...

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Detalles Bibliográficos
Autores principales: Zhao, Lei, Le Chapelain, Camille, Brachmann, Alexander O., Kaiser, Marcel, Groll, Michael, Bode, Helge B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248439/
https://www.ncbi.nlm.nih.gov/pubmed/33452852
http://dx.doi.org/10.1002/cbic.202100014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248439/
https://www.ncbi.nlm.nih.gov/pubmed/33452852
http://dx.doi.org/10.1002/cbic.202100014

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