D(1)- and D(2)-like receptors differentially mediate the effects of dopaminergic transmission on cost–benefit evaluation and motivation in monkeys

It has been widely accepted that dopamine (DA) plays a major role in motivation, yet the specific contribution of DA signaling at D(1)-like receptor (D(1)R) and D(2)-like receptor (D(2)R) to cost–benefit trade-off remains unclear. Here, by combining pharmacological manipulation of DA receptors (DARs...

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Detalles Bibliográficos
Autores principales: Hori, Yukiko, Nagai, Yuji, Mimura, Koki, Suhara, Tetsuya, Higuchi, Makoto, Bouret, Sebastien, Minamimoto, Takafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248602/
https://www.ncbi.nlm.nih.gov/pubmed/34197448
http://dx.doi.org/10.1371/journal.pbio.3001055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248602/
https://www.ncbi.nlm.nih.gov/pubmed/34197448
http://dx.doi.org/10.1371/journal.pbio.3001055

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