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D(1)- and D(2)-like receptors differentially mediate the effects of dopaminergic transmission on cost–benefit evaluation and motivation in monkeys
It has been widely accepted that dopamine (DA) plays a major role in motivation, yet the specific contribution of DA signaling at D(1)-like receptor (D(1)R) and D(2)-like receptor (D(2)R) to cost–benefit trade-off remains unclear. Here, by combining pharmacological manipulation of DA receptors (DARs...
Autores principales: | Hori, Yukiko, Nagai, Yuji, Mimura, Koki, Suhara, Tetsuya, Higuchi, Makoto, Bouret, Sebastien, Minamimoto, Takafumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248602/ https://www.ncbi.nlm.nih.gov/pubmed/34197448 http://dx.doi.org/10.1371/journal.pbio.3001055 |
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