Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host

Trypanosoma brucei rhodesiense is one of the causative agents of Human African Trypanosomiasis (HAT), known as sleeping sickness. The parasite invades the central nervous system and causes severe encephalitis that is fatal if left untreated. We have previously identified ecotin-like inhibitors of se...

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Detalles Bibliográficos
Autores principales: Levy, David Jessula, Goundry, Amy, Laires, Raquel S. S., Costa, Tatiana F. R., Novo, Carlos Mendes, Grab, Dennis J., Mottram, Jeremy C., Lima, Ana Paula C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248637/
https://www.ncbi.nlm.nih.gov/pubmed/34153047
http://dx.doi.org/10.1371/journal.pntd.0009526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248637/
https://www.ncbi.nlm.nih.gov/pubmed/34153047
http://dx.doi.org/10.1371/journal.pntd.0009526

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