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lra: A long read aligner for sequences and contigs

It is computationally challenging to detect variation by aligning single-molecule sequencing (SMS) reads, or contigs from SMS assemblies. One approach to efficiently align SMS reads is sparse dynamic programming (SDP), where optimal chains of exact matches are found between the sequence and the geno...

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Detalles Bibliográficos
Autores principales: Ren, Jingwen, Chaisson, Mark J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248648/
https://www.ncbi.nlm.nih.gov/pubmed/34153026
http://dx.doi.org/10.1371/journal.pcbi.1009078