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lra: A long read aligner for sequences and contigs
It is computationally challenging to detect variation by aligning single-molecule sequencing (SMS) reads, or contigs from SMS assemblies. One approach to efficiently align SMS reads is sparse dynamic programming (SDP), where optimal chains of exact matches are found between the sequence and the geno...
Autores principales: | Ren, Jingwen, Chaisson, Mark J. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248648/ https://www.ncbi.nlm.nih.gov/pubmed/34153026 http://dx.doi.org/10.1371/journal.pcbi.1009078 |
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