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Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility

The role of common genetic variation in susceptibility to acute myeloid leukemia (AML), and myelodysplastic syndrome (MDS), a group of rare clonal hematologic disorders characterized by dysplastic hematopoiesis and high mortality, remains unclear. We performed AML and MDS genome-wide association stu...

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Detalles Bibliográficos
Autores principales: Wang, Junke, Clay-Gilmour, Alyssa I., Karaesmen, Ezgi, Rizvi, Abbas, Zhu, Qianqian, Yan, Li, Preus, Leah, Liu, Song, Wang, Yiwen, Griffiths, Elizabeth, Stram, Daniel O., Pooler, Loreall, Sheng, Xin, Haiman, Christopher, Van Den Berg, David, Webb, Amy, Brock, Guy, Spellman, Stephen, Pasquini, Marcelo, McCarthy, Philip, Allan, James, Stölzel, Friedrich, Onel, Kenan, Hahn, Theresa, Sucheston-Campbell, Lara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248805/
https://www.ncbi.nlm.nih.gov/pubmed/34220922
http://dx.doi.org/10.3389/fgene.2021.554948